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New cancer immunotherapy approach combines tumor fighting power with fewer...

Basic research into the dual nature of certain immune system cells has set the stage for a new approach to cancer immunotherapy that avoids some of the shortcomings associated with other methods,...

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Closer to the source of the itch

Psoriasis is an inflammatory skin condition that affects some 125 million people worldwide. It is characterized by itchy, scaly skin plaques. The exact cause of psoriasis is unclear. But mounting...

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Scientists investigate how the gut influences mood

Scientists are investigating how bacteria in the gut might affect our mood, as part of a new study being carried out at Nottingham Trent University.

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Immune breakthrough: Unscratching poison ivy's rash

We all know that a brush with poison ivy leaves us with an itchy painful rash. Now, Monash University and Harvard researchers have discovered the molecular cause of this irritation. The finding brings...

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New study links protein in wheat to the inflammation of chronic health...

Scientists have discovered that a protein in wheat triggers the inflammation of chronic health conditions, such as multiple sclerosis, asthma and rheumatoid arthritis, and also contributes towards the...

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Genomic testing could speed research on skin disease and bring new drugs to...

In an ideal world, the newest and most effective drugs for chronic inflammatory conditions would immediately help everyone who took them. Unfortunately, in the real world, it can take several months to...

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New drug target for inflammatory disease is all the RAGE

Researchers have shown that Receptor for Advanced Glycation End Products (RAGE) helps to regulate a key signaling pathway known to promote both acute and chronic inflammation. The development of...

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Protein build-up may trigger inflammation associated with Alzheimer's and...

A recent review article published online in The FASEB Journal points to the "trigger" for the inflammatory response, caused by the immune system, that precedes Alzheimer's disease and other...

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Exercise... It does a body good: 20 minutes can act as anti-inflammatory

It's well known that regular physical activity has health benefits, including weight control, strengthening the heart, bones and muscles and reducing the risk of certain diseases. Recently, researchers...

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Curb your immune enthusiasm

Normally when we think of viruses, from the common cold to HIV, we want to boost people's immunity to fight them. But for scientists who develop therapeutic viruses (to, for example, target cancer...

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Pinpointing the mechanisms that underlie emotional responses to pain

Pain serves as a warning signal to indicate the intensity and location of damage to the body. In addition to unpleasant sensations, painful events trigger negative emotional responses that may serve to...

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Researchers provide evidence linking 'leaky gut' to chronic inflammation

With the help of genetically engineered mice, scientists at the Massachusetts General Hospital (MGH) are moving closer to establishing the role that increased intestinal permeability, sometimes called...

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White wine may do no favors for a woman's skin

(HealthDay)—Could that glass of Chardonnay affect the condition of your skin?

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Cellular stress increases the probability of developing autoimmune diseases

A team of researchers led by Marc Veldhoen at the Instituto de Medicina Molecular (iMM), Lisboa, has found that cellular stress enhances the activation of immune cells implicated in many chronic...

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Taking medications as prescribed important to control health care costs

At a time when health care costs are scrutinized more closely than ever, a new study demonstrates the importance of taking medications as prescribed to control costs.

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Targeting 'broken' metabolism in immune cells reduces inflammatory disease

The team, led by researchers at Imperial College London, Queen Mary University of London and Ergon Pharmaceuticals, believes the approach could offer new hope in the treatment of inflammatory...

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New target could soothe the itch of inflammatory skin conditions

Existing medicines could offer a new way to treat inflammatory skin conditions, researchers at the Walter and Eliza Hall Institute and the Royal Melbourne Hospital have revealed.

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Study finds harmful protein on acid triggers a life-threatening disease

Using an array of modern biochemical and structural biology techniques, researchers from Boston University School of Medicine (BUSM) have begun to unravel the mystery of how acidity influences a small...

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New insights into protein's role in inflammatory response

A protein called POP2 inhibits a key inflammatory pathway, calming the body's inflammatory response before it can become destructive, Northwestern Medicine scientists have demonstrated in mouse models.

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Could painkillers be hiding serious arthritis condition from doctors?

Thousands of patients with an inflammatory arthritis condition might be being mis-diagnosed because the pain killers they take hide the problem from doctors.

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What happens to your body when you're stressed

We all feel stressed from time to time – it's all part of the emotional ups and downs of life. Stress has many sources, it can come from our environment, from our bodies, or our own thoughts and how we...

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Etosis phenomenon discovered in human blood monocytes

A recent study published online in the Journal of Leukocyte Biology found the first clear demonstration of etosis in human blood monocytes, a type of immune cell. Etosis, a phenomenon previously...

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Expensive drug driving up Medicare expenditures without evidence of greater...

Medicare spent more than $1 billion over a five-year period on a high-priced drug that has not been proven more effective for a collection of inflammatory conditions than much less expensive...

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Drug targeting could aid immune diseases

A new technique that targets drugs to specific cells could lead to improved therapies for diseases caused by an overactive immune response. The approach could help people affected by conditions such as...

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Researchers find common mutation in the genetics behind eczema

Everyone who has ever had to endure eczema knows just how irritating the symptoms are. Now A*STAR researchers have pinpointed a genetic predisposition to the condition, opening possibilities for new...

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Rheumatoid arthritis linked to an increased risk of COPD

New research suggests that rheumatoid arthritis may increase the risk of developing chronic obstructive pulmonary disease (COPD). The findings, which appear in Arthritis Care & Research, indicate...

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Researchers uncover link between immune function and osteoarthritic pain and...

The immune system plays a pivotal role in the amount of pain and disease progression experienced by patients with osteoarthritis (OA), McMaster University researchers have found.

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Dysfunctional gene may be culprit in some Crohn's disease cases

This holiday season, millions of people will gather at airports ready to board planes for destinations around the world. Depending on the environment at their destination, their suitcases may be filled...

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Researchers discover key driver of atopic dermatitis

Severe eczema, also known as atopic dermatitis, is a chronic inflammatory skin condition that is driven by an allergic reaction. In their latest study, researchers at La Jolla Institute reveal an...

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Searching for targeted treatments for inflammatory diseases

Inflammatory diseases such as Crohn's disease and multiple sclerosis have been linked to faults in a critical immune pathway that enables inflammation to continue unchecked.

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